gPROMS FormulatedProducts 2.2 – new version boasts usability enhancements and new bioprocessing libraries

LONDON, 15 September 2021 --- Siemens Process Systems Engineering (SPSE), recently released gPROMS FormulatedProducts 2.2, the mechanistic modelling environment for integrated digital design of robust formulated products and their manufacturing processes, and related digital process operation.

gPROMS FormulatedProducts 2.2 brings a host of usability enhancements in addition to a substantial number of additions and enhancements to existing libraries, examples, and documentation.

Dialogs for gPROMS activities, such as simulation, model validation, and optimisation, have been simplified to show only the most relevant process parameters and attributes. Commonly controlled and measured variables, key trajectories, and estimated parameters are now highlighted for each unit operation when configuring these entities and exploring results. Further improvements have been made to gPROMS FormulatedProducts’ Global System Analysis capabilities, including the addition of contour plots, highlighting features and the ability to include one step re-simulate for a specific realization.

Version 2.2 also introduces key library enhancements and new models in active ingredient manufacture, formulation manufacture and product performance. New models include a basic stirred tank reactor, addition of LLE thermodynamics, moisture content controller, solid density sensor, and a spray dryer with internal fluid bed. Enhancements in this release include increased flowsheeting support for the Morphological MSMPR crystallizer, modifications to the continuous direct compression models, and improvements to wet granulators.

After the launch of gPROMS FormulatedProducts’ bioprocessing capability earlier in 2021, version 2.2 expands and builds on the model libraries for this evolving sector with new and enhanced models available for bioreactor control systems, product quality attributes, tangential flow filtration, disc stack centrifugation, radial flow chromatography, and whole bioprocess modelling.

SPSE continues to lead innovation in advanced process modelling capabilities for the pharmaceuticals, food & beverage, consumer goods and specialty chemicals sectors through the support of industrial and academic partners, funded development projects such as NextGen DDaMM, D-DAP, DIDCOM-FP, and the Systems-based Pharmaceutics Alliance.