gPROMS FormulatedProducts
Features & advantages
gPROMS FormulatedProducts® contains many features for Active Ingredient Manufacture, Product manufacture and product performance.
Mechanistic models
gPROMS FormulatedProducts contains models for all of the operations and activities listed below.
| Synthesis and Crystallization | ||
|---|---|---|
| Well-mixed reactor Plug flow reactor Well-mixed crystallizer |
Plug flow crystallizer Wet mill Pressure filter |
Filter dryer |
| Solids Processing | ||
| Dry mill Roller compactor Agglomerator High shear wet granulator Twin screw granulator Fluid-bed granulation 2D pop balance granulation framework |
Fluid-bed drying Spray drying Hot melt extruder Lyophilization |
Tablet press Conveying Tablet coater Continuous blenders Film coater Bin flow / segregation |
| Product Performance | ||
| In-vitro dissolution and precipitation Oral absorption in GI tract |
Pharmacokinetics Stability |
|
| Bioprocessing | ||
| Bioreactor Fermentor Axial flow chromatography Simulated moving bed chromatography Membrane filtration Lyophilization |
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The models are logically grouped into the libraries shown on the gPROMS FormulatedProducts product sheet
Global System Analysis capabilities
Explore and quantify the effects of uncertainty, for example in raw materials quality, using Global System Analysis techniques.
Data import tool
The gPROMS FormulatedProducts data import tool allows you to import a data file of any form.
Through this interface, you can open your data file, select data, and link it to your gPROMS variables.
You can also do some data processing and filtering, like only accepting data from certain time points, smoothing your data, or removing outliers.
Once you’re finished, you can export this to gPROMS to create the performed experiment entity. You can also create templates for this, so if your data always comes in a certain format, you only need to go through this process once.
